Hot and cold exposure is called hormesis, and in our case “Hormesis Therapy”. Hormesis is a characteristic of many biological processes, namely a biphasic or triphasic response to exposure to increasing amounts of a substance or condition. [1] Within the hormetic zone, the biological response to low exposures to hypo or hyper-thermia, toxins and other stressors is generally favorable. The term comes from the ancient Greek hormáein “to set in motion. In this course we will dive into the benefits of Heat and cold exposure, the amount of time and temperatures for maximum benefit.